Prior to trying out thesixtyone.com I had never heard of the following bands and artists:
Bandwagon Device (from Saskatchewan)
Dust Rhinos (from Winnipeg)
Paul and Storm
The Avett Brothers (who are downright awesome)
I came across all of them, and more, in the past 48 hours. Based on how I heard about the site (via an overenthusiastic advertising guy) I was skeptical about what I'd find, but it turns out there are a lot of great independent artists out there. I've mostly been listening to the folk channel includes lots of bluegrass and acoustic stuff too) as well as the rock, alternative and pop channels. The nice thing about the site is that a lot of the artists provide song to download for free, which puts thesixtyone.com way ahead of most other online radio and music sites.
You can check out what I've found below.